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PEP-Therapy extends Series-A financing, raising a total of €5.4 million to progress the clinical development of its lead candidate PEP-010

Institut Curie
07/19/2021
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Institut Curie’s spin-off PEP-Therapy announced today that it raised an additional €2.6 million in an extension of its Series A financing round, bringing the total raised in this round to €5.4 million. This increased financial support highlights the potential of PEP-010, as well as PEP-Therapy’s Cell Penetrating & Interfering Peptide (CP&IP) technology platform, which was first developed at Sorbonne University and Institut Curie. The biotechnology company develops cell penetrating peptides as targeted therapies for the treatment of cancers.
PEP-Therapy

Spin-off from Institut Curie founded in 2014, PEP-Therapy announced today that it raised an additional €2.6 million in an extension of its Series A financing round, bringing the total raised in this round to €5.4 million. This new funding comprises €1.6 million in equity from Anaxago, i&i Prague and BADGE as well as a €1 million loan from Bpifrance. The biotechnology company develops cell penetrating peptides as targeted therapies for the treatment of cancers.

PEP-010 is the first of a new class of therapeutic peptides based on PEP-Therapy’s innovative Cell Penetrating & Interfering Peptide (CP&IP) technology. These innovative molecules penetrate cells and specifically block relevant intracellular protein-protein interactions, leading to the inhibition of key pathological mechanisms, without altering physiological mechanisms.

 

With this Series A funding, PEP-Therapy will finance the Phase I a/b clinical trial of PEP-010, PEP-Therapy’s lead candidate, for the treatment of advanced solid tumors. The first part of the Series A, which closed in April 2021, will finance the Phase Ia dose escalation part of the study, with the additional funds being used for the development of PEP-010 until the end of the expansion cohorts, Phase Ib.

PEP-Therapy expects to generate promising clinical data from this study, particularly in two indications: metastatic triple negative breast cancer and platinum resistant ovarian cancer. Patients with these two types of solid tumors have a poor prognosis and limited therapeutic alternatives.

 We are delighted to have completed this financing round via an attractive balance of dilutive and non dilutive-funds from new high quality and diversified investors who will bring expertise and new insights to support our development.

said Antoine Prestat, CEO and co-founder of PEP-Therapy.

In addition, PEP-Therapy and its clinical partners, Institut Curie and Gustave Roussy, previously received a €2.9 million grant from the French state innovation fund – Fonds Unique Interministériel (FUI) – to finance nonclinical and early clinical development of PEP-010.

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